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China Best Supplier Pharmaceutical Intermediate 2-Methylimidazole 2-Methyl-1h-Imidazole CAS 693-98-1

Product Name: 2-Methylimidazole
Synonyms: 2-Methyl-1H-imidazole
Short Name: 2MI
Cas No.: 693-98-1
EINECS: 211-765-7
Molecular Formula: C4H6N2
Assay (%):99
Availability:
Quantity:
  • 2-Methylimidazole

  • SINOBIO

  • 293329

Pharmaceutical Intermediate 2-Methylimidazole CAS 693-98-1



2-Methylimidazole (CAS 693-98-1) is an organic compound with the molecular formula C₄H₆N₂, belonging to the imidazole family. Below is a structured overview of its key properties and applications:


Physical and Chemical Properties


*Appearance: White to light yellow crystalline powder or needle-like crystals.

*Molecular Weight: 82.10 g/mol.

*Melting Point: 142–145 °C.

*Boiling Point: 267–268 °C.

*Solubility:

-Highly soluble in water (780 g/L at 20 °C), ethanol, and ketones.

-Insoluble in cold benzene and ether.

*Density: 1.03–1.05 g/cm³.

*pH (100 g/L, 20 °C): 10.5–11.5 (alkaline).

*Stability: Stable under normal conditions but may decompose at high temperatures or in strong acids/bases.


2-Methylimidazole, as a key chemical intermediate, holds significant application value in the pharmaceutical and feed industries: Firstly, it serves as the core intermediate for synthesizing the drug methylprednisolone (Medrol) and is also a crucial raw material for producing the feed growth promoter dimethazole; Second, in the field of polymer materials, this substance can serve as a curing component for epoxy resins and other resin types, demonstrating particularly outstanding performance in epoxy resin curing systems.


As a medium-temperature curing agent for epoxy resins, 2-methylimidazole can be used independently. However, in industrial practice, its primary application is as a curing accelerator in powder molding processes and powder coating production, effectively enhancing curing efficiency and product performance stability.


Regarding physicochemical properties, 2-methylimidazole exhibits significant hygroscopicity, necessitating moisture-proof storage measures. Solubility-wise, it dissolves readily in polar solvents like water and ethanol but is poorly soluble in non-polar solvents such as benzene. Special caution is warranted as 2-Methylimidazole exhibits significant irritant and corrosive properties. Direct contact with skin or mucous membranes may cause adverse reactions including redness, swelling, and burns. Professional protective equipment must be worn during handling.


Beyond these applications, 2-Methylimidazole is extensively used in synthesizing the anti-anaerobic drug metronidazole. Within epoxy resin curing systems, it functions not only as a standalone curing agent but is also frequently blended with other curing components to optimize the resin's mechanical properties and resistance to chemical media.



Technical Data Sheet (TDS):


Product  Name 2-Methylimidazole
CAS 693-98-1
Other names 1H-Imidazole,2-methyl-;2-methyl-1h-imidazol;2-methyl-imidazol;
Molecular  Formula C4H6N2
Molecular  Weight 82.1
Apperance white to light yellow crystalline powder
Purity 99%



2-Methylimidazole Application:


1. Pharmaceutical Industry

*Acts as an intermediate in the synthesis of nitroimidazole antibiotics (e.g., metronidazole, tinidazole), which are used to treat anaerobic bacterial and parasitic infections.

*Serves as a building block for biologically active compounds, including drugs and ligands in coordination chemistry.


2. Polymer and Resin Industry

*Functions as a curing agent and accelerator for epoxy resins, enhancing cross-linking in semiconductor potting compounds and solder masks.

*Used in powder coatings and molding applications to improve thermal stability and mechanical properties.


3. Coordination Chemistry

*Acts as a ligand to simulate histidine coordination in heme complexes, forming imidazolate-based polymers.


4. Other Uses

*Catalyst for protein refolding (e.g., enhanced fluorescent proteins).

*Auxiliary agent in textile dyes and industrial chemicals.



Package and Shipping:


Standard Package: 25kg/Drum. We provide customized package for different quantity.


Shipping: By sea or By air or Express

SINOBIO cooperate with different shipping company to help customer arrange the shipping for different quantity.


Payment: T/T, western union , moneygram or as your requirement.



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