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99.5% Industrial Grade Propylene Glycol Wetting Agent Food/Pharmaceutical

Product Name: Propylene Glycol PG
CAS: 57-55-6
Chemical formula: C3H8O2
Appearance: Colorless viscous liquid
Availability:
Quantity:
  • Propylene Glycol 99.5%

  • SINOBIO

  • 2905320000


Product Overview


99.5% Industrial Grade Propylene Glycol is a versatile aliphatic dihydric alcohol with FDA-compliant food-grade and pharmaceutical-grade certifications, manufactured through advanced catalytic hydrogenation of propylene oxide. Renowned for its hygroscopic properties (absorbing up to 50% of its weight in moisture) and excellent solubility in water and organic solvents (including alcohols, esters, and ketones), this colorless, odorless liquid serves as a critical wetting agent, emulsifier, and humectant across industries. Its low toxicity (LD50 >20g/kg in oral rat tests) and biocompatibility make it ideal for applications requiring strict safety standards, such as food preservation, pharmaceutical formulations, and personal care products. Unlike glycerin, it offers better freeze-thaw stability, making it a preferred choice in cold-chain applications.


Product Specifications


Parameter

Value

Purity

≥99.5% (GC)

Appearance

Clear, colorless liquid

Density @ 25°C

1.036–1.038 g/cm³

Boiling Point

188.2°C

Flash Point

107°C (closed cup)

pH

5.0–7.0

Solubility

Miscible with water, ethanol

Viscosity @ 20°C

42.5 mPa·s

Water Content

≤0.2%


Features


Food-Grade Safety:

Complies with FCC (Food Chemicals Codex) 9th Edition and Halal standards (certified by IFANCA).

Prevents caking in powdered foods like seasonings and dairy products by maintaining optimal moisture levels (3–5% water activity).

Acts as a humectant to maintain moisture in baked goods, extending shelf life by 30–50% compared to untreated products.

Resists microbial growth in low-water formulations due to its low redox potential.


Pharmaceutical Applications:

Enhances drug solubility in liquid formulations (e.g., syrups, injectables) by up to 400% for hydrophobic APIs like ibuprofen.

Serves as a cryoprotectant in cell preservation, maintaining >90% cell viability after 6 months of cryostorage at -80°C.

Non-irritating and non-toxic, meeting USP/NF (United States Pharmacopeia/National Formulary) Monograph <1,551> requirements for residual solvents.

Compatible with common excipients including cellulose derivatives, sugars, and surfactants.


Industrial Performance:

Low volatility (vapor pressure <0.1 mmHg @ 20°C) ensures stability in high-temperature processes up to 150°C.

Anti-freezing properties (freezing point -59°C) make it suitable for deicing solutions and coolant formulations in industrial machinery.

Biodegradable (98% degradation within 28 days per OECD 301B test) and environmentally friendly with no bioaccumulation potential.


Applications


Food Industry

Baked Goods: Maintains moisture in bread, cakes, and cookies by forming hydrogen bonds with starch molecules, preventing staleness and textural degradation.

Beverages: Acts as a solvent for flavors and colorants in carbonated drinks, juices, and functional beverages, ensuring uniform dispersion even during long-term storage.

Confectionery: Reduces sugar crystallization in candies and chocolates by interfering with sucrose molecular alignment, maintaining smooth texture for 6–12 months.

Dairy Products: Stabilizes emulsions in ice cream (prevents ice crystal formation) and yogurt (maintains creamy consistency during shelf life).


Pharmaceutical Sector

Oral Medications: Enhances the solubility of hydrophobic active ingredients in suspensions, syrups, and oral gels, improving bioavailability by 20–30%.

Topical Formulations: Used in creams and lotions as a moisturizer and penetration enhancer, increasing skin absorption of actives like vitamin C and retinol by 1.5–2x.

Vaccine Production: Protects antigens during freeze-drying processes, preserving vaccine efficacy for up to 24 months at 2–8°C.


Personal Care & Cosmetics

Skincare: Adds long-lasting hydration to creams, serums, and shampoos by forming a protective film that reduces transepidermal water loss (TEWL) by 30%.

Fragrances: Solubilizes essential oils in perfumes and colognes, preventing phase separation and ensuring consistent scent profiles.

Makeup: Prevents drying in lipsticks and mascaras by maintaining optimal moisture balance, extending product usability by 2–3 months.


Industrial Use Cases

Textiles: Improves dye penetration by 25% and reduces static in fabric processing through its hygroscopic properties, enhancing color fastness.

Paints & Coatings: Acts as a film-forming agent and anti-freeze additive, preventing cracking in water-based paints during cold weather application.

Agriculture: Enhances the efficacy of pesticides and herbicides through improved wetting of leaf surfaces, reducing runoff by 15–20%.


Bulk Price Organic Solvent USP Grade Propyleneglycol CAS 57-55-6  Bulk Price Organic Solvent USP Grade Propyleneglycol CAS 57-55-6

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