Email : zhou@sinobiochemistry.com Phone : +86-13941198570
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IPBC 99%
SINOBIO
29241900
99% IPBC (Iodopropynyl Butylcarbamate) is a broad-spectrum antimicrobial agent with excellent fungal and yeast control (MIC 0.1–1 ppm), widely used in cosmetics, paints, and wood preservatives. This white crystalline powder operates through inhibition of fungal ergosterol synthesis, disrupting cell membrane integrity in target organisms. Offering low volatility (vapor pressure <0.001 mmHg @ 25°C) and high stability under acidic to neutral conditions (pH 4–9), it provides cost-effective preservation against microbial spoilage. Its low toxicity (LD50 >5,000 mg/kg in oral rat studies) and compatibility with anionic, cationic, and non-ionic surfactants ensure safe and efficient preservation across diverse formulations. Unlike formaldehyde releasers, it does not produce sensitizing byproducts during storage.
Parameter | Value |
Purity | ≥99% (GC) |
Appearance | White crystalline powder |
Melting Point | 55–57°C |
Density @ 25°C | 1.41 g/cm³ |
Solubility | 0.1 g/100mL (water); 50+ g/100mL in ethanol |
pH Stability | 4–9 |
Heavy Metals | ≤10 ppm |
Loss on Drying | ≤0.5% |
Residue on Ignition | ≤0.1% |
Microbial Control:
Fungal Suppressant: Inhibits Aspergillus niger, Candida albicans, and Penicillium chrysogenum at 0.01–0.05% concentration, achieving 6-log reduction in 72 hours.
Biofilm Prevention: Destroys extracellular polymeric substances (EPS) in coatings by 85% through disruption of polysaccharide matrices, extending service life by 2–3 years.
Long-Lasting Efficacy: Provides 6–12 months protection in cosmetics under recommended storage (25°C, 60% RH) with minimal degradation.
Synergistic Effects: Enhances activity of phenethyl alcohol and DMDM hydantoin by 30–50% when used in combination.
Regulatory Compliance:
Cosmetic Safety: Complies with EU Cosmetics Regulation (EC) 1223/2009 (maximum allowed concentration 0.05% in leave-on products) and FDA 21 CFR 352.15.
Industrial Use: Approved for wood preservation under ASTM D3458 (0.1–0.5% active) and paint formulations in ISO 15181-5 with migration limits <0.1 mg/kg.
Labeling Compliance: Meets global INCI naming requirements and California Prop 65 standards for low halogen content.
Formulation Flexibility:
Solvent-Free Systems: Effective in alcohol-based sprays (0.02–0.1%) and oil-in-water emulsions, with no phase separation observed in 3-month stability tests.
Cold Processing: Stable at ≤50°C, suitable for heat-sensitive formulations like vitamin C serums and enzyme-based products.
Color Compatibility: Does not cause yellowing in white or light-colored formulations, unlike some brominated preservatives.
Skin Care:
Preserves anti-aging creams (0.03–0.05% addition) and sunscreens (SPF 30+), preventing mold growth for 12 months in accelerated testing (40°C/75% RH).
Used in natural deodorants at 0.02–0.04% to inhibit odor-causing bacteria (Staphylococcus epidermidis) with 99% reduction in 24 hours.
Hair Care:
Stabilizes shampoos (0.02–0.03%) and conditioners, extending shelf life by 12–18 months without affecting foam stability.
Controls Malassezia yeast infections in dandruff treatments at 0.03–0.05% concentration, reducing flaking by 60% in 4 weeks.
Architectural Paints:
Prevents mildew growth on interior walls in humid climates when added at 0.1–0.3%, maintaining appearance for 5+ years in tropical environments.
Enhances color retention in exterior paints by inhibiting microbial degradation of binders, reducing fade by 40% compared to untreated paints.
Wood Coatings:
Protects timber floors and furniture from rot and blue stain fungi at 0.2–0.5% dosage, passing ASTM D3274 mold resistance testing.
Used in marine paints at 0.3–0.6% to resist biofouling in saltwater environments, reducing barnacle attachment by 70%.
Adhesives & Sealants:
Inhibits bacterial growth in water-based adhesives (0.1–0.2%), maintaining viscosity within 5% of initial values over 6 months.
Stabilizes silicone sealants used in construction joints at 0.05–0.1%, preventing mold-induced degradation in high-humidity areas.
Textiles:
Imparts anti-microbial properties to sportswear and medical fabrics through 0.05–0.1% topical application, achieving AATCC 100 rating (>99% reduction).
| Product Name | Iodopropynyl butylcarbamate IPBC |
| CAS NO | 55406-53-6 |
| Purity | 99% |
| Appearance | White powder not light yellow powder compared with Troy |
| Assay | ≥99.0%, higher assay compared with Troy |
| Melting point | 65.0-68.0ºC |
| Water content | 0.05% |
 |  |  |
99% IPBC (Iodopropynyl Butylcarbamate) is a broad-spectrum antimicrobial agent with excellent fungal and yeast control (MIC 0.1–1 ppm), widely used in cosmetics, paints, and wood preservatives. This white crystalline powder operates through inhibition of fungal ergosterol synthesis, disrupting cell membrane integrity in target organisms. Offering low volatility (vapor pressure <0.001 mmHg @ 25°C) and high stability under acidic to neutral conditions (pH 4–9), it provides cost-effective preservation against microbial spoilage. Its low toxicity (LD50 >5,000 mg/kg in oral rat studies) and compatibility with anionic, cationic, and non-ionic surfactants ensure safe and efficient preservation across diverse formulations. Unlike formaldehyde releasers, it does not produce sensitizing byproducts during storage.
Parameter | Value |
Purity | ≥99% (GC) |
Appearance | White crystalline powder |
Melting Point | 55–57°C |
Density @ 25°C | 1.41 g/cm³ |
Solubility | 0.1 g/100mL (water); 50+ g/100mL in ethanol |
pH Stability | 4–9 |
Heavy Metals | ≤10 ppm |
Loss on Drying | ≤0.5% |
Residue on Ignition | ≤0.1% |
Microbial Control:
Fungal Suppressant: Inhibits Aspergillus niger, Candida albicans, and Penicillium chrysogenum at 0.01–0.05% concentration, achieving 6-log reduction in 72 hours.
Biofilm Prevention: Destroys extracellular polymeric substances (EPS) in coatings by 85% through disruption of polysaccharide matrices, extending service life by 2–3 years.
Long-Lasting Efficacy: Provides 6–12 months protection in cosmetics under recommended storage (25°C, 60% RH) with minimal degradation.
Synergistic Effects: Enhances activity of phenethyl alcohol and DMDM hydantoin by 30–50% when used in combination.
Regulatory Compliance:
Cosmetic Safety: Complies with EU Cosmetics Regulation (EC) 1223/2009 (maximum allowed concentration 0.05% in leave-on products) and FDA 21 CFR 352.15.
Industrial Use: Approved for wood preservation under ASTM D3458 (0.1–0.5% active) and paint formulations in ISO 15181-5 with migration limits <0.1 mg/kg.
Labeling Compliance: Meets global INCI naming requirements and California Prop 65 standards for low halogen content.
Formulation Flexibility:
Solvent-Free Systems: Effective in alcohol-based sprays (0.02–0.1%) and oil-in-water emulsions, with no phase separation observed in 3-month stability tests.
Cold Processing: Stable at ≤50°C, suitable for heat-sensitive formulations like vitamin C serums and enzyme-based products.
Color Compatibility: Does not cause yellowing in white or light-colored formulations, unlike some brominated preservatives.
Skin Care:
Preserves anti-aging creams (0.03–0.05% addition) and sunscreens (SPF 30+), preventing mold growth for 12 months in accelerated testing (40°C/75% RH).
Used in natural deodorants at 0.02–0.04% to inhibit odor-causing bacteria (Staphylococcus epidermidis) with 99% reduction in 24 hours.
Hair Care:
Stabilizes shampoos (0.02–0.03%) and conditioners, extending shelf life by 12–18 months without affecting foam stability.
Controls Malassezia yeast infections in dandruff treatments at 0.03–0.05% concentration, reducing flaking by 60% in 4 weeks.
Architectural Paints:
Prevents mildew growth on interior walls in humid climates when added at 0.1–0.3%, maintaining appearance for 5+ years in tropical environments.
Enhances color retention in exterior paints by inhibiting microbial degradation of binders, reducing fade by 40% compared to untreated paints.
Wood Coatings:
Protects timber floors and furniture from rot and blue stain fungi at 0.2–0.5% dosage, passing ASTM D3274 mold resistance testing.
Used in marine paints at 0.3–0.6% to resist biofouling in saltwater environments, reducing barnacle attachment by 70%.
Adhesives & Sealants:
Inhibits bacterial growth in water-based adhesives (0.1–0.2%), maintaining viscosity within 5% of initial values over 6 months.
Stabilizes silicone sealants used in construction joints at 0.05–0.1%, preventing mold-induced degradation in high-humidity areas.
Textiles:
Imparts anti-microbial properties to sportswear and medical fabrics through 0.05–0.1% topical application, achieving AATCC 100 rating (>99% reduction).
| Product Name | Iodopropynyl butylcarbamate IPBC |
| CAS NO | 55406-53-6 |
| Purity | 99% |
| Appearance | White powder not light yellow powder compared with Troy |
| Assay | ≥99.0%, higher assay compared with Troy |
| Melting point | 65.0-68.0ºC |
| Water content | 0.05% |
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