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Chlorhexidine Diacetate 56-95-1
SINOBIO
29121900
Chlorhexidine Diacetate (Chlorhexidine Acetate, CAS 56-95-1) is a biguanide compound with broad-spectrum antibacterial activity. The key information and advantages are analyzed as follows:
*Molecular formula and structure: C₂₂H₃₀Cl₂N₁₀·2C₂H₄O₂ (or C₂₆H₃₈Cl₂N₁₀O₄, with variations in notation depending on the source), consisting of two chlorophenyl biguanide groups connected by a hexane bridge, with the acetate group conferring water solubility.
*Appearance: White or nearly white crystalline powder, odorless, with a bitter taste.
*Solubility: Solubility in water at 20°C is 1.9 g/100 ml; soluble in ethanol, slightly soluble in other organic solvents.
*Melting Point and Stability: Melting point 153–156°C; decomposes at 260–262°C; store in a light-protected, sealed container at low temperature (2–8°C).
Test Item | Standard Code |
Character | White or nearly white crystal powder,no smell,taste bitter Dissolve in ethanol,slightly soluble in water |
Identify | ① 、② 、④ should be positive reaction . |
The maximum absorption in the 260nm wavelength | |
P-chloroaniline | Should confirm the rule |
Related Substance | Should confirm the rule . |
Residue on ignition | Less than 0.1% |
Assay Chlorhexidine Acetate |
More than 97.5% |
*Mechanism of action: By disrupting the structure of bacterial cell membranes, causing the leakage of intracellular substances, it rapidly kills Gram-positive bacteria (such as Staphylococcus aureus), Gram-negative bacteria (such as Escherichia coli), and fungi (such as Candida albicans), and is also effective against Pseudomonas aeruginosa.
*Clinical Applications: Widely used for skin disinfection, wound irrigation, surgical instrument disinfection, preoperative hand washing (soaking in a 0.02% aqueous solution for 3 minutes), and surgical site disinfection (using a 0.5% alcohol solution).
*Chemical stability: It remains stable under storage conditions (2–8°C). Avoid storing it with oxidizing agents or food-grade chemicals to prevent decomposition and the production of toxic nitrogen oxides and chlorine fumes.
*Application durability: Its cationic properties enable strong adsorption on skin or mucous membranes, ensuring prolonged disinfection efficacy.
*Medical field: Used for surgical instrument disinfection (0.1% aqueous solution containing 0.5% sodium nitrite for rust prevention) and skin wound disinfection (1% spray or 0.05% aqueous solution for rinsing).
* Gynecological Treatment: Compound formulations (containing chlorhexidine gluconate and metronidazole) are used for vaginal irrigation to treat vaginitis and abnormal vaginal discharge caused by bacteria, trichomonads, and fungi.
* Oral Care: Chlorhexidine compound mouthwash is used as an adjunctive treatment for gingivitis, pericoronitis, and other conditions.
*Research and industry: Used as an organic synthesis intermediate, chemical reagent, and disinfectant/preservative in laboratory research and industrial production.
Q1: What types of packaging are available for solid products based on value?
A1: We offer three types of packaging for solid products based on value: fiber drum, carton, and plastic woven bag/PP bag.
Q2: What are the common weight capacities for the packaging options?
A2: The common weight capacities are 25kg and 200kg for drums or IBC drums. Specifically, fiber drums and bags typically hold 25kg, while cartons hold 20kg.
Q3: What shipping methods are available for delivering the products?
A3: The products can be shipped by DHL, FedEx, UPS, by sea, or by air, according to the client's request.
Chlorhexidine Diacetate (Chlorhexidine Acetate, CAS 56-95-1) is a biguanide compound with broad-spectrum antibacterial activity. The key information and advantages are analyzed as follows:
*Molecular formula and structure: C₂₂H₃₀Cl₂N₁₀·2C₂H₄O₂ (or C₂₆H₃₈Cl₂N₁₀O₄, with variations in notation depending on the source), consisting of two chlorophenyl biguanide groups connected by a hexane bridge, with the acetate group conferring water solubility.
*Appearance: White or nearly white crystalline powder, odorless, with a bitter taste.
*Solubility: Solubility in water at 20°C is 1.9 g/100 ml; soluble in ethanol, slightly soluble in other organic solvents.
*Melting Point and Stability: Melting point 153–156°C; decomposes at 260–262°C; store in a light-protected, sealed container at low temperature (2–8°C).
Test Item | Standard Code |
Character | White or nearly white crystal powder,no smell,taste bitter Dissolve in ethanol,slightly soluble in water |
Identify | ① 、② 、④ should be positive reaction . |
The maximum absorption in the 260nm wavelength | |
P-chloroaniline | Should confirm the rule |
Related Substance | Should confirm the rule . |
Residue on ignition | Less than 0.1% |
Assay Chlorhexidine Acetate |
More than 97.5% |
*Mechanism of action: By disrupting the structure of bacterial cell membranes, causing the leakage of intracellular substances, it rapidly kills Gram-positive bacteria (such as Staphylococcus aureus), Gram-negative bacteria (such as Escherichia coli), and fungi (such as Candida albicans), and is also effective against Pseudomonas aeruginosa.
*Clinical Applications: Widely used for skin disinfection, wound irrigation, surgical instrument disinfection, preoperative hand washing (soaking in a 0.02% aqueous solution for 3 minutes), and surgical site disinfection (using a 0.5% alcohol solution).
*Chemical stability: It remains stable under storage conditions (2–8°C). Avoid storing it with oxidizing agents or food-grade chemicals to prevent decomposition and the production of toxic nitrogen oxides and chlorine fumes.
*Application durability: Its cationic properties enable strong adsorption on skin or mucous membranes, ensuring prolonged disinfection efficacy.
*Medical field: Used for surgical instrument disinfection (0.1% aqueous solution containing 0.5% sodium nitrite for rust prevention) and skin wound disinfection (1% spray or 0.05% aqueous solution for rinsing).
* Gynecological Treatment: Compound formulations (containing chlorhexidine gluconate and metronidazole) are used for vaginal irrigation to treat vaginitis and abnormal vaginal discharge caused by bacteria, trichomonads, and fungi.
* Oral Care: Chlorhexidine compound mouthwash is used as an adjunctive treatment for gingivitis, pericoronitis, and other conditions.
*Research and industry: Used as an organic synthesis intermediate, chemical reagent, and disinfectant/preservative in laboratory research and industrial production.
Q1: What types of packaging are available for solid products based on value?
A1: We offer three types of packaging for solid products based on value: fiber drum, carton, and plastic woven bag/PP bag.
Q2: What are the common weight capacities for the packaging options?
A2: The common weight capacities are 25kg and 200kg for drums or IBC drums. Specifically, fiber drums and bags typically hold 25kg, while cartons hold 20kg.
Q3: What shipping methods are available for delivering the products?
A3: The products can be shipped by DHL, FedEx, UPS, by sea, or by air, according to the client's request.
