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Cosmetic Grade Glyoxylic Acid 50% CAS 298-12-4 Glyoxylic Acid for Skin

Name: Glyoxylic acid
CAS: 298-12-4
Chemical formula: C2H2O3
Appearance: Colorless Transparent Liquid
Availability:
Quantity:
  • Glyoxylic acid 50%

  • SINOBIO

  • 29183000

Sinobio Factory Supply Glyoxylic Acid Liquid



Basic Information


Product Name: Glyoxylic Acid

CAS Number: 298-12-4

Molecular Formula: C₂H₂O₃

Molecular Weight: 74.04

EINECS Number: 206-058-5

Other Names: Oxoacetic Acid, Formylformic Acid, Glyoxylic Acid, Glyoxylic Acid


Physical Properties


Appearance: Colorless to pale yellow, transparent liquid (pure product is colorless or pale yellow).

Odor: Has a disagreeable odor.

Melting Point: -93°C (anhydrous melting point: 98°C).

Boiling Point: 111°C.

Density: 1.33 g/mL (20°C).

Solubility:

Miscible with water, forming stable aqueous solutions.

Slightly soluble in ethanol, ether, and benzene. Insoluble in esters and aromatic solvents.

pH: 0.3 (19.5°C, aqueous solution).

pKa: 3.18 (25°C).



Glycolic Acid Chemical Properties


Melting point -93°C
Boiling point 111°C
Density 1.33 g/mL at 20 °C
Vapor pressure 14hPa at 19.85ºC
Refractive index n20/D 1.414
Fp 111°C
Storage temp. Store below +30°C.
Solubility Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters.
Pka 3.18(at 25ºC)
Form clear liquid
Color Colorless to Light orange to Yellow



Glyoxylic Acid Uses


1. Pharmaceutical Intermediates:

*Used in the production of oral penicillin, vanillin, ethyl vanillin, allantoin, etc.

*Allantoin is an anti-ulcer drug and an intermediate for pharmaceutical products and daily chemicals. It can be further processed into trace amounts of high-efficiency liquid fertilizers.


2. Spices and Flavors:

*Used as a flavoring and fixative in cosmetics.

*Used in flavorings for daily chemicals and food.


3. Dyes and Plastics:

*Used as an intermediate in dyes and plastics, participating in organic synthesis reactions.


4. Pesticide Intermediates:

*Used in the synthesis of pesticide raw materials and supporting the production of agricultural chemicals.


5. Other Applications:

*Also used in water stabilizers and mineral processing (as a hydroxyl group collector for flotation).



Glyoxylic Acid Advantage


Glyoxylic acid (CAS 298-12-4), an organic compound with both aldehyde and acid properties, demonstrates significant advantages in multiple fields, including the following:


1. Flavoring and Cosmetics: A natural alternative, enhancing product value

* Natural Vanillin Synthesis: Glyoxylic acid reacts with guaiacol to produce ethyl vanillin, whose aroma is more similar to natural vanilla. It is widely used in high-end cosmetics (such as perfumes and creams) and food flavorings, meeting consumer demand for "clean label" products.

* Skin Care Innovation: As an allantoin precursor, glyoxylic acid derivatives can promote keratinocyte renewal and strengthen the skin barrier function. They also possess antibacterial and moisturizing properties, making them core ingredients in anti-aging and sensitive skin care products.

* Hair Straightening Product Innovation: As a replacement for traditional sodium hydroxide in acidic hair straighteners, glyoxylic acid gently shapes hair by opening disulfide bonds, reducing hair damage and meeting the EU's stringent cosmetic safety requirements.


2. Agricultural Chemicals: Green Intermediates, Contributing to Sustainable Development

* Pesticide Intermediates: Glyoxylic acid is a key intermediate in the synthesis of herbicides such as glyphosate. Its high reactivity can shorten the synthesis route and reduce production costs.

* Plant Growth Regulators: By regulating the glyoxylic acid cycle in plants, it enhances photosynthesis efficiency, promotes crop stress resistance, and reduces fertilizer use.

* Biodegradable Materials: As a comonomer in polylactic acid (PLA), glyoxylic acid improves material flexibility while maintaining biodegradability, promoting the greening of agricultural packaging materials.


3. Industrial Applications: Versatility Expands Applications

* Water Stabilizers: Glyoxylic acid forms stable chelates with calcium and magnesium ions to prevent scale deposition and is widely used in boiler water treatment and cooling circulation systems.

* Varnish Raw Materials: Its aldehyde groups can undergo condensation reactions with alcohols to produce resins with excellent weather resistance. They are used in high-end wood coatings and automotive varnishes to enhance product gloss and hardness. 

*Dye intermediates: Key structural units involved in the synthesis of reactive and acid dyes. By regulating the reactivity of the aldehyde group, they enable highly selective binding of dye molecules to fibers.


4. Market and Process Advantages: Driving Industry Growth

*Market Expansion: The global glyoxylic acid market is projected to grow from US$500 million in 2024 to US$800 million in 2033, at a compound annual growth rate of 6%, primarily driven by demand in the pharmaceutical and beauty and personal care sectors.

*Process Innovation: A new process for catalyzing the production of glyoxylic acid from biomass feedstocks (such as pyruvate) achieves a yield exceeding 85%, significantly reducing dependence on fossil feedstocks and aligning with carbon neutrality goals.

*Regional Opportunities: The Asia-Pacific market (particularly China) has become a core area of growing demand for glyoxylic acid due to accelerated urbanization and rising beauty consumption. Local companies are seizing high-end market share through technological upgrades.





Product Packaging


Glyoxylic acid package  Glyoxylic acid package  Glyoxylic acid package

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