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Factory Supply Molnupiravir Powder Eidd-2801/Mk4482 99% CAS 2492423-29-5

Name: EIdd-2801
CAS: 2492423-29-5
Chemical formula: C13H19N3O7
Appearance: White powder
Availability:
Quantity:
  • EIdd-2801

  • SINOBIO

  • 2934999090

Molnupiravir Powder Eidd-2801/Mk4482 99% CAS 2492423-29-5



EIDD-2801/MK4482 (Monabiravir) Basic Information


Chinese Name: Monabiravir

English Name: Molnupiravir

CAS Number: 2492423-29-5

Molecular Formula: C₁₃H₁₉N₃O₇

Molecular Weight: 329.31 g/mol

Appearance: White or off-white powder

Purity: 99% (Research Grade/Pharmaceutical Grade)

Solubility: Soluble in DMSO (with ultrasonic assistance required), slightly soluble in water.

Storage Conditions: Store in a sealed, light-protected container at -20°C (avoid repeated freeze-thaw cycles).



What is EIdd-2801 ?


Ridgeback announced that the US Food and Drug Administration (FDA) has approved the ind application for oral antiviral compound eidd-2801. The FDA's move allows Ridgeback to launch clinical trials of eidd-2801 in humans in the United States.


Eidd-2801 is an oral bioavailable form of highly effective ribonucleoside analogues, which can inhibit the replication of a variety of RNA viruses. The animal studies of two different coronaviruses showed that eidd-2801 could improve lung function, reduce weight loss and reduce the amount of virus in the lung.

EIDD-2801 is the isopropylester prodrug of N4-hydroxycytidine. With improved oral bioavailability in non human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5'-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe.



Technical Data Sheet (TDS):


Product Name
EIDD-2801
CAS
2349386-89
Appearance
White powder
MF
C13H19N3O
Molecular Weight
329.31
Purity
99% min
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder
Shelf Life
24 Months



EIDD-2801 Core Functions


1. Antiviral Mechanism

* As a ribonucleoside analog, it incorporates into the viral RNA chain by mimicking the nucleotides required for RNA virus replication.

* Induces lethal mutations (error mutations) during viral RNA replication, thus preventing viral replication and transmission.


2. Antiviral Spectrum

* Coronaviruses: SARS-CoV-2 (COVID-19), MERS-CoV, SARS-CoV.

* Influenza viruses: Seasonal influenza, pandemic influenza.

* Other viruses: Respiratory syncytial virus (RSV), Chikungunya virus, Ebola virus, etc.


3. Clinical Potential

* COVID-19 Treatment: Early clinical trials show it can shorten the course of the disease and reduce the risk of severe illness.

* Influenza Treatment: Effective against drug-resistant influenza virus strains, potentially becoming a novel anti-influenza drug.



EIDD-2801 Application Scenarios


1. Scientific Research

* Virology Research: Used to explore the replication mechanisms of RNA viruses and develop antiviral drugs.

* Animal Model Experiments: To evaluate the effects of drugs on viral load, lung function, and body weight changes.


2. Pharmaceutical Intermediates

* As a precursor for the synthesis of antiviral drugs (such as EIDD-1931).



Standard Package:


Packing: we can provide 1kg/bag, 25kg/drum. Different quantities have different packaging, according to your requirements


Shipping: by express DHL, FEDEX, TNT......or as your requirement


Payment: T/T,western union,moneygram or as your requirement


Eidd 2801  Eidd 2801


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