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Salicylamide
SINOBIO
2924299090
Product Name: Salicylamide, 2-Hydroxybenzamide
CAS No.: 65-45-2
EINECS No.: 200-609-3
Molecular Formula: C₇H₇NO₂
Molecular Weight: 137.14
Appearance: White / slightly pink crystalline powder, acicular crystals
Salicylamide (CAS 65-45-2), a high-purity crystalline powder with a minimum purity of 99% (pharmaceutical grade), is a versatile fine chemical integrating antipyretic, analgesic and intermediate properties.
It presents as white to slightly pink crystalline powder or acicular crystals, with stable chemical properties, easy storage and transportation, and is widely used in pharmaceutical, fine chemical, rubber and other fields.
As a core pharmaceutical intermediate, it is not only directly used as an antipyretic and analgesic drug for relieving fever, headache, neuralgia and other symptoms, but also an important raw material for synthesizing various drugs such as niclosamide and o-ethoxybenzamide.
In industrial fields, it serves as a key intermediate for organic synthesis (preparing fragrances, dyes, pesticides) and a rubber additive to improve rubber performance, with high application value and market potential.
*Direct Medical Use: Antipyretic and analgesic drug, used for fever, headache, neuralgia, arthralgia, active rheumatism, etc.
*Pharmaceutical Intermediate: Used in the synthesis of drugs such as niclosamide (molluscicide/antiparasitic drug) and o-ethoxybenzamide (analgesic).
*Pharmacological Research: Used as a microsomal UDP-glucuronosyltransferase inhibitor for drug metabolism research.
*Organic Synthesis: An important intermediate used in the preparation of fine chemicals such as fragrances, dyes and pesticides.
*Rubber Industry: Used as a rubber additive to improve rubber performance.
*Others: Used in combustion research, fuel additives, etc.
Item | Details |
|---|---|
Melting Point | 140–144 °C |
Boiling Point | 279.7 °C (760 mmHg) |
Density | 1.175 g/cm³ |
Solubility | Easily soluble in ethanol, ether, chloroform and hot water; slightly soluble in cold water; soluble in ammonia, NaOH and other alkaline solutions |
Aqueous Solution pH | About 5 (saturated solution at 28℃, acidic) |
Purity | Industrial grade ≥98%, Pharmaceutical grade ≥99% |
Storage Conditions | Sealed, stored in a cool and dry place (recommended to be stored in a cool and dark place below 15℃) |
LD₅₀ (Oral, Mouse) | 1.4 g/kg |
- High Gastrointestinal Safety: Stable and not decomposed in the stomach, with much less irritation to the gastric mucosa than aspirin.
- Stable Efficacy: Clear antipyretic, analgesic and anti-inflammatory effects, suitable for mild to moderate pain and fever.
- Good Compatibility: Can be compounded with a variety of drugs to expand clinical application scenarios.
- High Intermediate Value: The structure contains hydroxyl and amide groups, with rich reaction sites, suitable for various synthesis routes.
- Easy Purity Control: Mature synthesis process, easy to achieve high purity of ≥99%, meeting the requirements of pharmaceutical/high-end chemical industry.
- Controllable Cost: Easy access to raw materials, stable process, and high cost performance in large-scale production.
- Convenient Storage and Transportation: Stable at room temperature, easy to crystallize and package, reducing storage and transportation costs.
Packaging: 25kg/bag
Delivery time: 7-15 working days after receiving deposit, or as per customer requirements.