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Salicylamide Powder CAS 65-45-2 99% for Antipyretic Analgesic Rubber Additive

Product Name: Salicylamide, 2-Hydroxybenzamide
CAS No.: 65-45-2
EINECS No.: 200-609-3
Molecular Formula: C₇H₇NO₂
Molecular Weight: 137.14
Appearance: White / slightly pink crystalline powder, acicular crystals
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  • Salicylamide

  • SINOBIO

  • 2924299090

Salicylamide Powder CAS 65-45-2 99% for Antipyretic Analgesic Rubber Additive




Product Name: Salicylamide, 2-Hydroxybenzamide

CAS No.: 65-45-2

EINECS No.: 200-609-3

Molecular Formula: C₇H₇NO₂

Molecular Weight: 137.14

Appearance: White / slightly pink crystalline powder, acicular crystals


Salicylamide (CAS 65-45-2), a high-purity crystalline powder with a minimum purity of 99% (pharmaceutical grade), is a versatile fine chemical integrating antipyretic, analgesic and intermediate properties. 

It presents as white to slightly pink crystalline powder or acicular crystals, with stable chemical properties, easy storage and transportation, and is widely used in pharmaceutical, fine chemical, rubber and other fields.

As a core pharmaceutical intermediate, it is not only directly used as an antipyretic and analgesic drug for relieving fever, headache, neuralgia and other symptoms, but also an important raw material for synthesizing various drugs such as niclosamide and o-ethoxybenzamide.

In industrial fields, it serves as a key intermediate for organic synthesis (preparing fragrances, dyes, pesticides) and a rubber additive to improve rubber performance, with high application value and market potential.




Product Applications


1. Pharmaceutical Field (Core Application)


*Direct Medical Use: Antipyretic and analgesic drug, used for fever, headache, neuralgia, arthralgia, active rheumatism, etc.

*Pharmaceutical Intermediate: Used in the synthesis of drugs such as niclosamide (molluscicide/antiparasitic drug) and o-ethoxybenzamide (analgesic).

*Pharmacological Research: Used as a microsomal UDP-glucuronosyltransferase inhibitor for drug metabolism research.


2. Rubber Industry Additive

Used as high-efficiency rubber antioxidant and thermal stabilizer. It can effectively capture free radicals generated during rubber processing and long-term use, inhibit thermal oxidative aging, cracking and discoloration of rubber products, and significantly extend the service life of tires, rubber hoses, sealing parts and synthetic rubber materials.


3. Fine Chemical & Organic Synthesis

Important synthetic intermediate for salicylic acid derivatives, dyes, spice compounds and surfactant raw materials. It can undergo acylation, alkylation and condensation reactions to synthesize various high-value fine chemical products.


4. Other Industrial Fields

Used as raw material for cosmetic anti-inflammatory additives, pesticide intermediates and laboratory analytical reagents, with wide industrial adaptability.


Item
Standard Parameter
Product Name
Salicylamide / 2-Hydroxybenzamide
CAS No.
65-45-2
Molecular Formula
C₇H₇NO₂
Molecular Weight
137.14
EINECS No.
200-609-3
HS Code
2924299090
Appearance
White fine crystalline powder
Purity
≥99.0%
Melting Point
139℃ - 142℃
Loss on Drying
≤0.5%
Residue on Ignition
≤0.1%
Heavy Metal (Pb)
≤10ppm
Solubility
Slightly soluble in water, soluble in ethanol, ether, hot organic solvents
Transport Attribute
Non-dangerous goods, no UN number required





1. High Purity & Ultra-Low Impurity

Strict secondary recrystallization purification process ensures 99% minimum purity, effectively removes residual salicylic acid, inorganic salts and heavy metal impurities. Stable batch indicators fully meet pharmaceutical intermediate and industrial additive grade standards, avoiding formula failure caused by excessive impurities.

2. Dual Functional Value for Medicine & Industry

It has both pharmaceutical biological activity and industrial auxiliary properties. It can be used for antipyretic and analgesic drug synthesis, and also serves as high-efficiency rubber anti-aging agent, realizing dual-scenario application and improving raw material utilization rate.

3. Excellent Stability & No Discoloration

Pure crystalline structure with stable physical and chemical properties. No yellowing, agglomeration or deterioration during long-term sealed storage. Adaptable to conventional high-temperature processing and synthesis reaction conditions.

4. Good Solubility & Formula Compatibility

Good solubility in common organic solvents, uniform dispersion in pharmaceutical preparations and rubber formula systems. No precipitation, no stratification, no adverse impact on finished product color and performance.

5. Cost-Effective Industrial Intermediate

Stable factory supply with competitive pricing, suitable for large-scale industrial continuous production. Supports customized particle size and purity grading to meet different customer process requirements.

Packing: 25kg fiber drum / kraft paper bag, or customized packaging.

Storage: Keep container tightly closed, store in cool, dry and well‑ventilated warehouse, keep away from heat and direct sunlight.

Transport: Avoid heavy squeezing, rain and moisture during shipment.

Delivery time: 7-15 working days after receiving deposit, or as per customer requirements.

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