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N-(2-Hydroxyethyl)piperazine CAS 103-76-4 99.5% Pharmaceutical & Surfactant Intermediate

Name: N-(2-Hydroxyethyl)piperazine CAS 103-76-4 99.5% Pharmaceutical & Surfactant Intermediate
Brand: SINOBIO
Rating: 5.0 (23 reviews)

Product Name: N-(2-Hydroxyethyl)piperazine
Aliases: 1-(2-Hydroxyethyl)piperazine, N-Hydroxyethylpiperazine
CAS No.: 103-76-4
Molecular Formula: C₆H₁₄N₂O
Molecular Weight: 130.19

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Model:
N-(2-Hydroxyethyl)piperazine
Brand:
SINOBIO
Code:
2933599090

N-(2-Hydroxyethyl)piperazine CAS 103-76-4 99.5%

Pharmaceutical & Surfactant Intermediate

Product Name: N-(2-Hydroxyethyl)piperazine
Aliases: 1-(2-Hydroxyethyl)piperazine, N-Hydroxyethylpiperazine
CAS No.: 103-76-4
Molecular Formula: C₆H₁₄N₂O
Molecular Weight: 130.19

N-(2-Hydroxyethyl)piperazine, also known as 1-(2-Hydroxyethyl)piperazine, 1-Piperazineethanol or N-β-Hydroxyethylpiperazine (CAS Number: 103-76-4, Molecular Formula: C₆H₁₄N₂O, Molecular Weight: 130.19), is a high-performance organic chemical intermediate with excellent water solubility and reaction activity. As a professional manufacturer and supplier, we provide high-purity N-(2-Hydroxyethyl)piperazine (99%/99.5% grade) for global B2B customers, widely used in pharmaceutical, pesticide, surfactant, polyurethane coating, water treatment and other industrial fields. Our product is produced through advanced synthesis technology, with low impurities, stable performance and safe storage, fully meeting the strict requirements of industrial and pharmaceutical grade applications, and has won recognition from customers in Europe, America, Southeast Asia and other regions. Whether you need bulk procurement or customized specifications, we can provide one-stop supply solutions to help you reduce production costs and improve product competitiveness.

N-(2-Hydroxyethyl)piperazine (CAS 103-76-4) is a colorless to light yellow transparent liquid at room temperature, with a density of 1.061 g/mL (20℃), melting point of -38.5℃, boiling point of 246℃ (atmospheric pressure), and refractive index of 1.5065, which is easy to dissolve in water, methanol and other alcohol solvents, and incompatible with lipid solvents. Its unique molecular structure contains both hydroxyl and piperazine ring groups, which gives it excellent reaction selectivity and versatility, making it an indispensable key intermediate in fine chemical synthesis. Our N-(2-Hydroxyethyl)piperazine is produced by the reaction of piperazine hexahydrate and ethylene oxide, with strict quality control throughout the production process to ensure that the product purity reaches 99% or 99.5% above, and the content of harmful impurities is far lower than the industry standard, effectively avoiding side reactions in downstream production and improving product yield and quality. It has a low vapor pressure (0.0322mmHg at 25℃) and a flash point of 135℃, which is safe and convenient for storage and transportation in barrels (200kg/barrel).

Product Applications

As a versatile organic intermediate, N-(2-Hydroxyethyl)piperazine (CAS 103-76-4) is widely used in multiple industrial fields, covering pharmaceutical, pesticide, surfactant, polyurethane, water treatment and other key sectors, with broad application prospects and stable market demand:

1. Pharmaceutical Intermediate: It is the core raw material for synthesizing APIs (Active Pharmaceutical Ingredients), mainly used in the production of antihistamines, cardiovascular drugs, antipsychotic drugs (such as fluphenazine) and antibiotics intermediates, with high purity and good compatibility, fully meeting the GMP standards of the pharmaceutical industry, and providing reliable support for the research and production of pharmaceutical enterprises.

2. Pesticide & Fine Chemicals: As an important intermediate for pesticide synthesis, it is used to produce high-efficiency and low-toxicity pesticides, fungicides and plant growth regulators, which can effectively improve the activity and stability of pesticide products, reduce environmental pollution, and meet the requirements of modern green pesticide development.

3. Surfactants & Auxiliaries: It is used to prepare cationic, anionic and amphoteric surfactants, emulsifiers, corrosion inhibitors and desulfurization and decarbonization agents, which are widely used in oilfields, metal processing, textile printing and dyeing and other fields, and can significantly improve product performance and reduce production costs.

4. Polyurethane & Coating Auxiliaries: As a catalyst, crosslinking agent and chain extender for polyurethane, it can improve the curing speed of polyurethane products, enhance the hardness, adhesion and weather resistance of the paint film, and is suitable for the production of high-performance coatings, adhesives and foam products, meeting the high-standard requirements of industrial coatings and architectural coatings.

5. Buffer & Electrolyte: It is used as an additive for biological buffers, electroplating solutions and lithium battery electrolytes, which can effectively adjust the pH value of the system, improve the stability of the solution, and is widely used in laboratory research, electroplating industry and new energy battery fields.

6. Epoxy Resin Curing Agent: It can be used as a curing agent for epoxy resin, which can accelerate the curing speed, improve the chemical resistance and mechanical properties of epoxy resin products, and is suitable for the production of composite materials, electronic components and other products.

Properties	Values / Descriptions
Appearance	Colorless to light yellow transparent liquid
Density	1.061 g/mL (20℃)
Melting Point	-38.5 ℃
Boiling Point	246 ℃ (Atmospheric Pressure)
Refractive Index	1.5065
Flash Point	135 ℃
Solubility	Easily soluble in water, methanol and other alcoholic solvents; insoluble in lipid solvents

Compared with other suppliers of N-(2-Hydroxyethyl)piperazine (CAS 103-76-4) in the market, our products have obvious competitive advantages, focusing on solving the pain points of B-end customers such as unstable quality, high impurities and high procurement costs, and creating greater value for customers:

1. High Purity & Low Impurities: Industrial grade and pharmaceutical grade products are available, with purity up to 99% and 99.5% above, strict control of harmful impurities, no adverse impact on downstream reaction yield and product color, stable and consistent product quality, and small batch-to-batch difference, which is convenient for customers to use in large-scale production.

2. Excellent Reactivity & Selectivity: The molecular structure contains both hydroxyl and double nitrogen rings, with clear reaction sites, moderate reaction activity, not easy to produce side reactions, high reaction yield, suitable for fine synthesis and pharmaceutical grade production processes, effectively reducing customer production losses and improving production efficiency.

3. Superior Water Solubility & Compatibility: It is easily soluble in water and most alcohol solvents, and has good compatibility with various organic solvents, which can be applied to a variety of production systems, expanding the application scope of the product, avoiding the problem of poor solubility in the production process of customers, and reducing the use cost of auxiliary agents.

4. Stable Performance & Safe Storage and Transportation: It is a liquid at room temperature, not easy to decompose, non-flammable and non-explosive, with stable chemical properties, and can be stored for a long time under sealed and cool and dry conditions. The product is packaged in 200kg/barrel, which is convenient for bulk transportation and large-scale use, and reduces customer transportation costs.

5. Multifunctional Structure & High Cost-Effectiveness: It has multiple properties such as alkalinity, hydrophilicity and coordination, which can replace a variety of single-function auxiliaries, simplify the customer's production formula, reduce procurement costs and production costs, and improve the comprehensive competitiveness of the customer's products.

6. Environmentally Friendly & Low Toxicity: Compared with traditional amine auxiliaries, it has lower irritation, meets the environmental protection requirements of modern pharmaceutical, coating, water treatment and other industries, and complies with the environmental protection standards of various countries, which is convenient for customers to export products and expand the global market.

7. Factory Direct Supply & Competitive Price: We have our own professional production base, realizing direct supply from factory to customer, eliminating intermediate links, reducing customer procurement costs, and providing competitive bulk prices. At the same time, we can provide customized production according to the special requirements of customers (such as special purity, packaging specifications), and provide flexible supply solutions.