Email : zhou@sinobiochemistry.com Phone : +86-13941198570
Views: 0 Author: Site Editor Publish Time: 2025-07-04 Origin: Site
In the fields of life science research and biopharmaceuticals, the accuracy and reproducibility of experimental results are paramount. As a critical reagent for maintaining pH stability in reaction systems, the quality of buffer solutions directly impacts data reliability. Tris77-86-7-1 (Tris-HCl), a premium biological buffer designed for high-precision experiments, has become the global laboratory standard due to its exceptional purity and stability. As an industry-leading supplier, we are committed to delivering trusted solutions for research and industrial applications.
Tris77-86-7-1 is a white crystalline powder (molecular formula: C₄H₁₁NO₃) renowned for its superior buffering capacity (pH 7.0–9.0) and ultra-low metal impurities.
Key advantages include:
*Ultra-high purity: ≥99.9% (HPLC-verified), Trace element control:Heavy metals (Pb, Cd, Hg) < 0.001ppm,Iron ions (Fe³⁺) should be less than 1ppm to avoid interfering with enzyme reactions, meeting stringent requirements for cell culture and molecular biology.
*Precise Buffering: With a pKa value of 8.06, it perfectly covers the pH range of 7.0-9.0, adapting to the physiological environment of most biological systems (such as cell culture media and enzyme reaction systems).
*Broad Compatibility: Easily soluble in water (solubility of 100g/100mL at 20℃), it does not react with common biological molecules (DNA, proteins), avoiding interference with experimental results.
1.Biological Research: A core component of TAE/TBE electrophoresis buffers, supporting DNA fragment separation; maintaining pH stability in chromatographic columns during protein purification, facilitating monoclonal antibody research and development;
2.Pharmaceutical Industry: Used as a tromethamine salt raw material, it participates in the synthesis of ketorolac, prostaglandin drugs, and adjusts the pH of injection solutions to a physiologically compatible range (reducing vascular irritation);
3.Cosmetics: Balances the pH of formulations in creams and serums (preventing inactivation of fruit acids/vitamin C), while enhancing the stability of emulsification systems and improving product skin feel;
4.High-End Manufacturing: In wafer cleaning in the electronics industry, it serves as a buffer medium to control the acidity and alkalinity of etching solutions, reducing damage to chip surfaces.
With 18 years of focus on the research, development, and production of biological buffers, we offer more than just products—we provide customized solutions:
*Full Specification Coverage: From 100g small packages (for research) to 25kg cardboard barrels (for industrial mass production), supporting customization of 99.0% industrial grade, 99.5% molecular biology grade, and 99.9% pharmaceutical grade;
*Global Compliance Certification: Meets multiple pharmacopoeia standards such as USP41, EP, and GMP, with product access to over 30 countries, adapting to FDA and EMA regulatory requirements;
*Technical Expertise: Our dedicated R&D team can optimize formulations according to customers' experimental systems (such as low-temperature, high-salt environments), providing free sample testing and buffer system design consulting;
*Rapid Response: Sinobio combined with a global logistics network, also have free application optimization guidance.
Parameter | Tris77-86-7-1 | Standard Buffers |
Batch Consistency | CV <1% | Typically 3%–5% |
Endotoxin Levels | <0.03 EU/mg | 0.5–1 EU/mg |
Dissolution Time | 30 sec (20°C water) | 2–5 min stirring |
Whether it's precision experiments in gene sequencing laboratories or large-scale production in pharmaceutical factories, Tris is synonymous with stability and reliability. Choose us to make every innovative research free from worries.
If you have any questions about the product, please feel free to contact us !
