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Home » News » Industry News » PHMB 20%(Polyhexamethylene Biguanide 20% Aqueous Solution):High-Efficacy Broad-Spectrum Bactericidal Liquid Biocide with Multi-Scenario Application Advantages

PHMB 20%(Polyhexamethylene Biguanide 20% Aqueous Solution):High-Efficacy Broad-Spectrum Bactericidal Liquid Biocide with Multi-Scenario Application Advantages

Views: 0     Author: Site Editor     Publish Time: 2026-09-18      Origin: Site

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With  the  rapid  growth  of  industries  including   personal  care,  cosmetic  formulation,  water- based coatings, textile finishing, household disinfection, water treatment and industrial waterborne systems, problems such as  microbial contamination, bacterial  reproduction, mold spoilage,  product off- odor and  shortened   shelf- life  have  become  prominent.  Conventional  biocides  frequently   suffer  from insufficient  bactericidal  potency,  narrow  antimicrobial  spectrum,  high  irritation,  poor  compatibility with  surfactants,  instability  under  high  temperature,  heavy  metal  residues  or  strong  odor.  Many cosmetic,  home- care  and  industrial  projects  demand  low- irritation,  non- releasing,  high- efficiency liquid bactericides.


Against this industry background, PHMB 20%— a 20% active aqueous solution of Polyhexamethylene  Biguanide  —  emerges   as  a   benchmark  cationic  polymeric  biocide.  Featuring broad- spectrum bactericidal performance, low skin irritation, excellent water solubility, high thermal stability and outstanding cost- effectiveness,  it delivers  reliable one- stop antimicrobial solutions for cosmetics, disinfection, textiles, water treatment and multiple industrial segments.



Physical and Chemical Properties


PHMB 20% is an aqueous solution of Polyhexamethylene Biguanide hydrochloride (CAS: 32289- 58- 0). Its polymeric molecular structure grants distinctive physicochemical properties suitable for diversified industrial applications. Key specifications are shown below:


Standard Active Content and Strict Impurity Control

Active PHMB content: 20±1 %, water as solvent.  Free monomer and harmful residual impurities are strictly controlled; heavy- metal content  meets cosmetic- grade and industrial biocide requirements. Compliant  with  global  regulatory  standards  for  personal- care  articles,  textile  finishing  agents  and circulating water treatment.


Appearance and Excellent Water Miscibility

Appearance:   Clear  to   pale- yellow  transparent   liquid,   almost   odorless.   Specific  gravity   (20 °C):

1.04- 1.08 g/ mL,   raw  liquid  pH 4.0- 6.0.  Fully  miscible  with  water,   lower  alcohols  and  glycols;   no pre- dissolution  or  heating  required,  convenient  for  direct  addition   into  water- based   production systems.


Outstanding Thermal and pH Stability

Maintains  stable  bactericidal  activity  under  processing  temperature  up  to  90 °C,  applicable  for high- temperature textile finishing, coating thermal grinding and other thermal workflows.  Effective working pH range: 3.0- 9.5, keeps strong antimicrobial effect across acidic, neutral and weakly- alkaline environments. No precipitation under normal storage conditions; avoid long- term freezing.


Surface-affinity Characteristic and Compatibility Notes

It is a cationic polymer. Good compatibility with non-ionic and amphoteric surfactants;  incompatible with large-dose anionic surfactants, anionic polymers and anionic dyes,which may

cause flocculation or activity loss  .Without negative influence on product color and transparency when correctly formulated; can adsorb onto fiber and solid surfaces to obtain surface-lasting antibacterial performance.


PHMB 20% Polyhexamethylene Biguanide aqueous solution drums on pallet PHMB 20% aqueous solution drums loaded in shipping container




Core Action Mechanism:Multi-dimensional Antimicrobial Protection for Various Application Scenarios


PHMB 20% exerts bactericidal effects relying on its unique cationic polymeric biguanide structure.It does not rely on release of small-molecule irritant substances, and suppresses microbes via physical-chemical interaction with microbial cell membranes.


Positively-charged PHMB polymer chains are readily adsorbed onto negatively-charged bacterial, fungal and yeast cell surfaces. The polymer inserts into lipid layers of cell membranes,destroying membrane integrity, causing leakage of intracellular substances and resulting in rapid death of microbial cells.It inhibits reproduction of  Escherichia coli ,  Staphylococcus aureus ,  Candida albicans ,  Aspergillus niger  and various water-borne spoilage bacteria.


Thanks to its long-chain polymeric property,part of PHMB can adhere onto substrate surfaces such as textile fibers,forming a thin antibacterial layer and achieving residual surface bacteriostatic effect.It is non-corrosive to most equipment and base materials, low-odor, and will not produce irritating volatile decomposition products.It can be used alone or combined with other preservatives/biocides for synergistic efficacy,lowering overall biocide dosage and comprehensive formulation cost.



Wide Cross-Industry Applications:Broad-Spectrum Antimicrobial as Core,Covering Multiple High-value Sectors


Benefiting from 20% standardized liquid form, powerful bactericidal activity and surface- adsorption feature,  PHMB  20%  is  a  well- recognized  universal  liquid  biocide,  covering   personal- care,  textile, water- treatment,   household   disinfection   and   water- based   industrial   materials.    Recommended dosage varies for different fields:


1. Cosmetics & Personal- care Industry (0.05- 0.3 % dosage)

Suitable for  rinse- off and  leave- on  cosmetic  products:  body wash,  shampoo, wet wipes, skin- care lotion,  eye- care  products  and  low- irritation  cleansing  formulations.  It  inhibits  cosmetic  microbial contamination,   prevents   peculiar   smell   and   mildew,   extends   shelf- life;   meets   cosmetic   safety regulations for permitted usage of PHMB.


2. Textile Antibacterial Finishing Industry (0.2- 1.0 % dosage, based on bath weight)

Applied in antibacterial finishing of cotton, chemical- fiber fabrics, non- woven materials, masks and hygiene textiles. Adsorbs onto fiber surfaces to obtain durable antibacterial  performance;  restrains bacteria  breeding  on  textile  surfaces,   reduces  odor  generation  caused   by  sweat- decomposition, improves hygiene performance of finished textiles.


3. Industrial Water Treatment & Circulating Water (0.01- 0.1 % dosage)

Used for  cooling  circulating water, swimming  auxiliary  water,  industrial  process  water,  to  suppress bacteria,  algae  and  slime- forming   microorganisms;  reduces  pipeline  bio- fouling,  avoids  bacterial slime accumulation and equipment blockage, stabilizes water- system operation.


4. Household & Environmental Disinfection Products (0.1- 0.5 % dosage)

Used for surface disinfectants, hard- surface cleaning agents, sanitizing liquid for household articles. Effective against common  pathogenic bacteria,  provides safe surface sanitization with low- irritation characteristics.


5. Water- based Coatings, Adhesives & Other Waterborne Systems (0.08- 0.3 % dosage)

Applied in water- based coatings, polymer emulsions, leather processing auxiliaries. Controls bacterial spoilage  in  liquid  systems,  prevents  barrel  odour  and  slime  formation;  note:  avoid  heavy  anionic components in formula to prevent flocculation risk.



Significant Advantages Compared With Traditional Biocides


Compared  with  conventional   biocides  such  as  isothiazolinones   (MIT/CMIT),  DMDMH,  quaternary ammonium  salts  and  solid   PHMB   powder,  PHMB  20%  has  prominent  strengths   in  antimicrobial performance, safety, thermal stability and practical application:


1. Polymer- type non- volatile bactericide, higher safety performance

Unlike  formaldehyde- releasing   preservatives,   PHMB- 20%   does   not   release   formaldehyde.   Low skin- irritation risk; the 20% ready- to- use liquid avoids dust hazards existing in solid powder handling, and satisfies strict safety requirements for personal- care and hygiene- product manufacturing.


2. Broad- spectrum bactericidal plus surface- adsorbing lasting effect

Effective  against  bacteria,  yeast  and  partial  moulds.   Beyond  in- liquid   preservation,  its  cationic polymer  structure  enables  adsorption  onto  fiber  and  solid  surfaces  to  deliver  surface- residual antibacterial effect, a unique advantage not available for many small- molecule preservatives.


3. Excellent heat- resistance and wide pH adaptability

Stable at high temperature up to 90 °C, suitable for high- temperature processing conditions where isothiazolinones   will   decompose   and   lose   activity.   Maintains   good   efficacy   within   pH 3.0- 9.5, adaptable to diversified complex water- based formula environments.


4. Ready- to- use liquid, superior processing convenience & cost- effectiveness

Standard  20%  concentration  liquid,  direct  feeding  without  dissolution.  Compatible  with  automatic metering- feeding  systems  for  large- scale  production.  Can  be  used  independently  or  compounded with other biocides. One material serves multiple application fields, reducing raw- material inventory and comprehensive procurement cost.


>  Note: Special attention: incompatibility with  high- content anionic surfactants / anionic  polymers. Formulation compatibility pre- test is strongly recommended before mass production.



Choosing a Professional Supplier: Guarantee of High Quality and Stable Supply


DALIAN SINOBIO CHEMISTRY CO., LTD. is a specialized manufacturer engaged in R&D and production of biguanide- series bactericides and fine- chemical antimicrobial raw materials, a trusted supplier of high- quality PHMB 20 % aqueous solution. Relying on advanced polymerization synthesis technology, precise concentration- adjusting process and strict full- flow quality- control system, our  PHMB 20 % product features stable active content, low harmful residual monomers, clear liquid appearance and consistent batch- to- batch quality, exceeding ordinary commercial- grade standards.


We provide targeted technical guidance and formulation suggestion for cosmetics, textile finishing, water- treatment  and  disinfection- product  manufacturers.  Supported  by  mature  supply- chain  and complete  after- sales  service   system,  we  guarantee  stable  continuous  supply,  and   help  global customers solve core pain- points including microbial contamination and product quality deterioration. We   deliver   one- stop   fine- chemical   antimicrobial   raw- material   solutions   with    premium- grade products and professional- level services.



Looking for a Reliable PHMB 20% Supplier?


Looking for a reliable PHMB 20% manufacturer and supplier for cosmetics, textile finishing, water treatment, disinfection or water-based industrial applications? DALIAN SINOBIO CHEMISTRY CO., LTD. provides PHMB 20% aqueous solution with stable active content, controlled residual monomers, consistent batch quality and professional technical support. We can also provide formulation guidance and application suggestions according to your specific requirements.


Contact us today for PHMB 20% specifications, quotation, samples and technical support. Let us help you find a suitable antimicrobial raw material solution for your application.



DALIAN SINOBIO CHEMISTRY CO., LTD.

TEL & FAX: +86- 411- 8479 6919

E- mail: zhou@sinobiochemistry.com

Website: www.sinobiochemistry.com


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